Liz Cheney’s resounding primary defeat marks the end of an era for the Republican Party as well as her own family legacy, the most high-profile political casualty yet as the party of Lincoln transforms into the party of Trump.

The fall of the three-term congresswoman from Wyoming, who has declared it her mission to ensure Donald Trump never returns to the Oval Office, was vividly foreshadowed earlier this year, on the first anniversary of the Jan. 6 attack on the Capitol.

As the House convened for a moment of silence, Cheney, who is leading the investigation into the insurrection as vice chair of the 1/6 committee, and her father, former Vice President Dick Cheney, stood almost alone on the Republican side of the House floor.

Democratic lawmakers streamed by to shake their hands. Republicans declined to join them.

“Liz Cheney represents the Republican Party as it used to be. ... All of that is gone now,” said Geoff Kabaservice, vice president of political studies at the center-right Niskanen Center.

What comes next for Liz Cheney is still to be determined.

“Now the real work begins,” she said in an election night concession speech in Wyoming, summoning the legacy of both Abraham Lincoln and his Civil War-era military and presidential successor Ulysses Grant in her campaign against Trump.

Cheney could very well announce her own run for the White House — unlikely to win a hostile Republican Party’s nomination but to at least give those opposed to Trump an alternative.

Overnight, she transferred leftover campaign funds into a new entity: “The Great Task.” That’s a phrase from The Gettysburg Address.

“I will be doing whatever it takes to keep Donald Trump out of the Oval Office,” Cheney told NBC’s “Today” show early Wednesday. Pressed, she said that running for president “is something I’m thinking about and I’ll make a decision in the coming months.”